Medical devices

FlowSense Clinical / ACE

Clinical wearable and DSP/ML workflow for noninvasive CSF shunt-flow assessment; improved from a 74% baseline to 0.81 AUC / 82% blinded validation accuracy.

Part of Senior R&D Engineer · Rhaeos, Inc. · May 2022 – Dec 2025

completed 2022–2025 Medical devicesAlgorithmsValidationThermal sensing
Type product / algorithm
Skills Wearable sensing, Thermal physiology, ML/DSP, Clinical validation

Selected facts

Quantitative details and source-backed proof points.

Expert / Gen1 baseline: 74% accuracy.

FlowSense Gen2 blinded clinical validation: 0.81 AUC / 82% accuracy.

Final FlowSense + imaging framing: 92% sensitivity / 97% NPV.

Multicenter clinical workflow reference: 9 hospitals, 182 subjects, and a 112-subject validation set.

Deck-reported CT/MRI workflow reference: 88.9% sensitivity and 91.0% accuracy.

Supported 3,000+ hours of physiological/device data and 200+ HA Connect datasets across Rhaeos programs.

Workflow included ingestion, provenance, labeling, QC, dataset versioning, feature generation, validation, bias checks, explainability, and deployment checks.

Deployment work included MATLAB-to-TypeScript random-forest conversion with deterministic output checks.

Project summary

Why it exists, what I built, and what I learned.

Why I built it

Clinical shunt-flow assessment needed repeatable model development from noisy thermal physiology instead of manual thresholds alone.

What I built

Automated ingestion, provenance, labeling, QC, dataset versioning, feature generation, validation, bias checks, explainability, and deployment-check workflows.

What worked

The strongest result was connecting sensor physics, clinical usability, small-dataset controls, and deterministic deployment checks into one regulated workflow.

What failed

Small, correlated clinical datasets required patient grouping, leakage checks, bias review, feature-correlation checks, and overfitting controls.

What I learned

Physiological ML is strongest when feature design, validation, and deployment checks stay grounded in sensing physics and clinical workflow constraints.

Stack

Tools, systems, and technical areas involved.

Thermal sensingFeature engineeringMATLABPythonTypeScript deployment checksValidationFDA-ready documentation

Links and direction

Public links and next steps.

Next Future direction

Use the same sensor-physics-first validation pattern for adjacent wearable physiological monitoring problems.

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